Gene interactions and pathways from curated databases and text-mining

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PGC — TFAM

Text-mined interactions from Literome

Hickey et al., J Am Soc Nephrol 2011 (Anoxia...) : Conversely, inhibition of IHG-1 expression decreased mitochondrial mass, downregulated mitochondrial proteins, and PGC-1a regulated transcription factors, including nuclear respiratory factor 1 and mitochondrial transcription factor A ( TFAM ), and reduced activity of the TFAM promoter
Zhao et al., Hear Res 2013 (Genetic Predisposition to Disease...) : Furthermore, the overexpression of PGC-1a induced by transfection largely increased the expression levels of NRF-1 and TFAM and significantly decreased the expression level of NF-?B in the cell senescence model