Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
FOXO3
→
RAF1
(increases)
Evidence: Strikingly, Raf activation triggered the activation of FOXO proteins with the same rapid kinetics (48 hr) observed for the suppression of PI3K/AKT (Figure 6C).
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
IRef Intact Interaction:
Complex of 143 proteins
(association, anti tag coimmunoprecipitation)