Gene interactions and pathways from curated databases and text-mining

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ABL1 — PARP1

Text-mined interactions from Literome

Courtney et al., Eur J Neurosci 1999 : The death is accompanied by cleavage of the caspase substrate poly ADP ribose polymerase ( PARP ) and c-Abl dependent activation of the stress activated protein kinases c-Jun N-terminal kinase and p38
Mizuchi et al., Biochem Biophys Res Commun 2005 : BCR/ABL activates Rap1 and B-Raf to stimulate the MEK/Erk signaling pathway in hematopoietic cells ... Here we demonstrate that the inducible expression of BCR/ABL in a murine hematopoietic cell line, TonB210, leads to the activation of the Ras family small GTPase Rap1 , which is inhibited by the ABL kinase inhibitor imatinib
Nolz et al., J Cell Biol 2008 : The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G mediated activation of Rap1