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HSPG2 — PGF

Text-mined interactions from Literome

Arroyo et al., Placenta 2004 : PlGF induced similar activation of Nck and PLC-gamma in trophoblast and HUVEC
Gobbetti et al., Cell Signal 1993 : PLA1, PLA2, PLC , PKC and DAGlipase inhibitors induced a decrease in PGF2 alpha production in interrenals without mGnRH, and PLA2 inhibitor was more effective than other inhibitors
Breshnahan et al., Proc Soc Exp Biol Med 1996 : This indicates that PKC negatively modulates PGF2alpha induced PI-PLC activation, and that the late sustained DAG generation in response to PGF2alpha is regulated by a PKC dependent phospholipase other than PLC ... The mechanisms of PI-PLC stimulation in response to PGF2alpha were further explored using inhibitors of protein tyrosine phosphorylation and of guanine nucleotide binding ( G ) protein activation ... The observations indicate that PGF2alpha stimulates a PI-PLC which is under negative feedback regulatory control by PKC, and a phospholipase other than PLC which is under positive regulatory control by PKC ... PGF2alpha induced PI-PLC activation is independent of protein tyrosine phosphorylation and of PTx-sensitive G proteins