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BMP4 — PCBD1

Text-mined interactions from Literome

Cuervo et al., Dev Biol 2002 (Cleft Palate) : However, BMP-7 was unable to activate cell death within the palate tissue and NOGGIN, a natural BMP antagonist, did not block PCD
Traister et al., Cell Death Differ 2004 : Here, we demonstrate that bone morphogenetic protein-4 (BMP-4) , which is expressed in the ectoderm and dorsal NT at these developmental stages, induces programmed cell death (PCD) and promotes entry into the S-phase, via nitric oxide synthase (NOS) activity ... Ectopic BMP-4 induction of PCD is restricted to the dorsal NT, whereas promotion of the S-phase is evenly observed across the dorsal-ventral ( D-V ) axis
Pajni-Underwood et al., Development 2007 : We conclude that during normal embryogenesis, BMP signaling to the AER indirectly regulates interdigit PCD by regulating AER-FGFs, which act as survival factors for the interdigit mesenchyme