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EGF — IFI44

Text-mined interactions from Literome

Takeyama et al., J Immunol 2000 (MAP Kinase Signaling System) : Here we show that oxidative stress causes ligand independent activation of epidermal growth factor receptors (EGFR) and subsequent activation of mitogen activated protein kinase kinase ( MEK ) -p44/42 mitogen activated protein kinase ( p44/42mapk ), resulting in mucin synthesis in NCI-H292 cells
Fabregat et al., Hepatology 2000 : We show here that EGF activates p42 and p44 mitogen activated protein kinases ( MAPK )
van Rossum et al., J Biol Chem 2001 (MAP Kinase Signaling System) : p42/44(MAPK) in response to epidermal growth factor was not only phosphorylated via the Raf-MEK pathway but mainly through protein kinase C ( PKC ) or a related or unrelated kinase in which the phosphorylated p42/44(MAPK) corresponded with cPLA(2) activity
Martin et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Collectively, these findings indicate that IGFBP-3 enhances EGF signaling and proliferative effects in breast epithelial cells via increased EGF receptor phosphorylation and activation of p44/42 and p38 MAP kinase signaling pathways
Horikawa et al., Invest Ophthalmol Vis Sci 2003 : To compare activation of the p42/p44 mitogen activated protein kinase ( MAPK ) by cholinergic agonists and epidermal growth factor (EGF) in cultured human and rat goblet cells
Gui et al., J Biol Chem 2003 (MAP Kinase Signaling System) : In response to treatment with EGF, the EGF receptor was phosphorylated, which was correlated with phosphorylation and activation of p42/44 mitogen activated protein kinases
Raspaglio et al., Oncol Res 2003 (Carcinoma, Squamous Cell...) : Mitogen activated protein kinase ( MAPK ) analysis revealed that in Hep2 cells, but not in CO-K3 cells, EGF induced a time dependent phosphorylation of p42, p44 , p38, and p46
Arnoletti et al., J Gastrointest Surg 2004 (Adenocarcinoma...) : Likewise, EGF dependent phosphorylation of MAPK p44/42 was blocked by Erbitux treatment in MIA PaCa-2 but not BxPC-3 cells
Mata et al., Thorax 2005 : Roflumilast also inhibited the EGF induced expression of phosphotyrosine proteins, EGF receptor, and phospho-p38- and p44/42-MAPK measured by Western blot analysis in A549 cells
Heo et al., Cell Physiol Biochem 2006 : EGF also increased phosphorylation of p38 MAPK and p44/42 MAPKs, which was blocked by genistein or bisindolylmaleimide I, respectively
Lee et al., Am J Physiol Gastrointest Liver Physiol 2006 (MAP Kinase Signaling System) : In particular, EGF increased the translocation of PKC isoforms ( PKC-alpha, -beta ( 1 ), -gamma, -delta, and -zeta ) from the cytosol to the membrane fraction and increased the activation of p44/42 MAPK, p38 MAPK, and JNK
Lee et al., J Cell Biochem 2006 : Indeed, EGF increased the translocation of PKC from the cytosol to the membrane fraction, and increased the activation of p44/42 MAPK, p38 MAPK, and JNK
Capó-Aponte et al., Cell cycle (Georgetown, Tex.) 2007 : The KCC inhibitor [ ( dihydroindenyl ) oxy ] alkanoic acid ( DIOA ) and KCC activator N-ethylmaleimide ( NEM ), suppressed and enhanced EGF induced p44/42MAPK activation, respectively
Harwood et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Higher concentrations of rapamycin ( > or =100 ng/ml ) were required to inhibit epidermal growth factor (EGF) induced phosphorylation of p44/42 ( Thr ( 202 ) )
Park et al., Cell Prolif 2008 (Calcium Signaling) : EGF induced phosphorylation of p38 and p44/42 MAPKs, and this was blocked by SB 203580 ( a p38 MAPK inhibitor ) and PD 98059 ( a p44/42 MAPK inhibitor ), respectively
Suh et al., J Cell Physiol 2009 : Interleukin-6 promotes 2-deoxyglucose uptake through p44/42 MAPKs activation via Ca2+/PKC and EGF receptor in primary cultured chicken hepatocytes
Jeon et al., Lung Cancer 2010 (Carcinoma, Non-Small-Cell Lung) : In cholesterol depleted cells, EGF induced phosphorylation of Src, Akt, and p44/42 in the detergent-insoluble fraction were inhibited whereas phosphorylation of GSK-3beta was unaffected
Nakashima et al., Molecular cancer 2011 (Carcinoma...) : In addition, EGF induced phosphorylation of p44/p42 mitogen activated protein kinase and Akt were also enhanced by Y27632 or ROCK-siRNA
MacKenzie et al., Biochem J 1997 : Previous studies have shown that the activation of p44 and p42 mitogen activated protein ( MAP ) kinases ( ERK1 and ERK2 ) by growth hormone (GH) and phorbol esters, but not by epidermal growth factor , in 3T3-F442A preadipocytes is dependent on protein kinase C ( PKC )
Aplin et al., J Cell Sci 1999 : These data indicate that a limited degree of adhesion mediated cytoskeletal organization and focal adhesion complex formation are required for efficient EGF activation of p42 and p44-MAPKs