Gene interactions and pathways from curated databases and text-mining

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IL6 — PAEP

Text-mined interactions from Literome

Alvarez et al., Ann Hepatol 2007 (Liver Cirrhosis...) : However, danazol + PEG-IFN + ribavirin reduced the expression of IL-6 , IL-10, tumor necrosis factor alpha and transforming growth factor ss. Bone-marrow DNA content was not altered by any treatment
Lee et al., Fertil Steril 2010 : Glycodelin-A increased the secretion of interleukin-6, interleukin-13 , and granulocyte-macrophage colony stimulating factor from natural killer cells in the peripheral blood but does not affect their viability, cell death, and cytotoxicity ... Glycodelin-A increased the secretion of interleukin-6 , interleukin-13, and granulocyte-macrophage colony stimulating factor from natural killer cells in the peripheral blood but does not affect their viability, cell death, and cytotoxicity
Lee et al., J Biol Chem 2012 (MAP Kinase Signaling System) : Glycodelin-A stimulates interleukin-6 secretion by human monocytes and macrophages through L-selectin and the extracellular signal regulated kinase pathway
Liu et al., Nanoscale 2012 : PEG @ AuNPs enhanced LPS induced production of NO and IL-6 and inducible nitric oxide synthase (iNOS) expression in RAW264.7 cells, partially by activating p38 mitogen activated protein kinases ( p38 MAPK ) and nuclear factor-kappaB pathways
Pockley et al., Immunology 1990 : The effect of human placental protein 14 (PP14) on the production of interleukin-1 from mitogenically stimulated mononuclear cell cultures
Laird et al., Hum Reprod 1994 : The effect of interleukin 1 (IL1) and placental protein 14 (PP14) on the production of interleukin 6 (IL6) by cultured human endometrial epithelial cells prepared from endometrial biopsy material obtained at different stages in the menstrual cycle was investigated ... PP14 ( 1-50 micrograms/ml ) also caused a dose dependent increase in IL6 production by epithelial cells prepared from secretory endometrium, but had no effect on IL6 production by cells prepared from proliferative endometrium ... This suggests that PP14 and IL1 act via different mechanisms in the stimulation of IL6 production