Bobe et al., Blood 2001
(Agammaglobulinemia) :
In conclusion, these results demonstrate that in mouse megakaryocytes, CRP leads to PI 3-kinase dependent translocation of PLCgamma2 and Btk that are independent of one another, whereas thrombin only induces translocation of Btk through a pathway that is independent of PI 3-kinase activity
Chi et al., J Immunol 2002
(Calcium Signaling) :
Human C-reactive protein (CRP) at acute phase levels of 10-200 microg/ml triggered the phosphorylation of FcgammaRIIa, Syk kinase, and phospholipase Cgamma2 in granulocytic HL-60 cells