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FCGR2A — PLCG2
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
FCGR2A
→
PLCG2
(reaction)
Carpenter et al., Exp Cell Res 1999, Sekiya et al., J Biol Chem 2004, Dusi et al., Biochem Biophys Res Commun 1994, Law et al., Mol Cell Biol 1996
-
Reactome Reaction:
FCGR2A
→
PLCG2
(indirect_complex)
Sekiya et al., J Biol Chem 2004, Dusi et al., Biochem Biophys Res Commun 1994, Law et al., Mol Cell Biol 1996
Text-mined interactions from Literome
Thai et al., Blood 2003
(Calcium Signaling) :
Coengagement of Fc gamma RIIa and PECAM-1 resulted in negative regulation of
Fc gamma RIIa mediated
phospholipase C gamma 2 activation, calcium mobilization, and phosphoinositide 3-kinase dependent signaling pathways
Gratacap et al., J Biol Chem 1998
:
We propose that PI 3-kinase and its product PtdIns ( 3,4,5 ) P3 play a key role in the activation and adequate location of
PLCgamma2 induced by
FcgammaRIIA cross linking