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EIF4EBP1 — IRF6

Text-mined interactions from Literome

Potter et al., J Surg Res 2001 : Inhibition of both the p42/p44 MAPK pathway ( PD 98059 ) and the p38 MAPK pathway ( SB 203580 ) failed to alter LPS induced 4E-BP1 phosphorylation ... LPS stimulates 4E-BP1 phosphorylation in macrophages through FRAP/mTOR signaling
Lang et al., J Cell Physiol 2005 : In contrast, to the abovementioned results with leucine, LPS did not prevent the ability of pharmacological levels of IGF-I to phosphorylate 4E-BP1 , S6K1, mTOR or alter the availability of eIF4E
Seo et al., J Pharm Pharmacol 2005 : LPS increased the phosphorylation of p70 S6 kinase, but not 4E-BP1 , in a time dependent manner, and BST204 inhibited it in a dose dependent manner
Lang et al., Am J Physiol Endocrinol Metab 2010 (Body Weight...) : Finally, whereas LPS impaired the ability of leucine to stimulate muscle protein synthesis and 4E-BP1 phosphorylation in WT mice, this inflammatory state rendered mTOR ( +/- ) mice leucine unresponsive