◀ Back to MMP7
MMP1 — MMP7
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Yokoyama et al., Aliment Pharmacol Ther 2000
(Helicobacter Infections...) :
Whereas
MMP-1 was not detected in media from fibroblasts or H. pylori culture alone,
MMP-1 was
detected in cocultures ( P < 0.01 )
Sundstrom et al., AIDS Res Hum Retroviruses 2001
(Cardiomyopathies...) :
Low levels of constitutively expressed MMP-1 and -2 were detected in individual cultures of HMVEC-C and PBMCs. NE did not
induce MMP or TIMP expression by HMVEC-C and caused modest increases ( 3- to 4-fold ) in MMP-1 and -2 by uninfected PBMCs. Increased levels of NE-induced
MMP-1 ( 5-fold ) and MMP -2 ( 15-fold ) were detected in cocultures of HMVEC-C and uninfected PBMCs. HIV infection enhanced MMP-1 ( 46-fold ) and MMP-2 ( 48-fold ) and active MMP-7 ( 33-fold ) and MMP-9 ( 50-fold ) by PBMCs. Coculture of HIV infected PBMCs with HMVEC-C increased MMP-1 ( 110-fold ) and MMP-2 ( 307-fold ) but not active MMP-7 and -9
Suzuki et al., Exp Toxicol Pathol 2001
(Fibrosis) :
In conclusion, these findings suggest that the activity of MMPs may bealtered by
MMP-1 downregulation and
inhibition of
MMP activity by PAl-1 and TIMP-1 generated from tubular epithelial cells
Gillette et al., Tumori 2003
:
We
detected MMP-7 , urokinase plasminogen activator (uPA) and PAI-1 in both Matrigels, TIMP-2 was detected only in regular Matrigel and no
MMP-1 or TIMP-1 was detected in either matrix
Tan et al., Am J Respir Cell Mol Biol 2006
(Pneumonia...) :
No increases in RNA levels of MMP-2,
MMP-9 , or MMP-8 were found, but levels of
MMP-7 , MMP-12, and MMP-13 RNA did
increase at 14 d
Dozier et al., Med Chem 2006
:
Whether the additional collagenases,
MMP-8 and MMP-13, are also
activated by
MMP-7 has not been explored
Bogatkevich et al., Arthritis Rheum 2007
(MAP Kinase Signaling System...) :
Inhibition of MMP activity by
MMP inhibitor GM1489 and
inhibition of
MMP-1 expression by siRNA did not prevent HGF induced ERK-1/2 phosphorylation and NF-kappaB activity, but significantly restored HGF inhibited collagen and CTGF accumulation
La et al., J Periodontol 2009
:
Grape seed extract suppresses lipopolysaccharide induced
matrix metalloproteinase ( MMP ) secretion by macrophages and
inhibits human
MMP-1 and -9 activities
Wang et al., Gynecol Oncol 2011
(Neoplasm Invasiveness...) :
Furthermore,
MMP-1 and PAR1 were both significantly
induced by LPA ( 20 µM ), and siRNA silencing of
MMP-1 and PAR1 both significantly reduced LPA 's invasion promoting effect in DOV13 cells ( p < 0.05 )
Yuan et al., Zhongguo Gu Shang 2012
(Osteoarthritis, Knee) :
Western blotting showed that beta-catenin, MMP-7 expression in OA synoviocytes was significantly higher than normal group, Bushen Huoxue decoction could significantly reduce beta-catenin,
MMP-7 expression ; ELISA results showed that MMP-7 expression of OA synovial supernatant was significantly higher than normal synoviocytes supernatant, Bushen Huoxue decoction significantly
regulated the level
MMP-7 down