Gene interactions and pathways from curated databases and text-mining

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MMP1 — WNT5A

Text-mined interactions from Literome

Masckauchán et al., Mol Biol Cell 2006 : Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2
Ge et al., Arthritis Rheum 2009 : To determine the possible involvement and regulatory mechanisms of Wnt-5A signaling in interleukin-1beta (IL-1beta) induced increase in matrix metalloproteinase 1 (MMP-1) , MMP-3, MMP-9, and MMP-13 expression in temporomandibular joint ( TMJ ) condylar chondrocytes ... SP600125, a JNK inhibitor, was used to investigate the role of the JNK pathway in Wnt-5A induction of MMP-1 , MMP-3, MMP-9, and MMP-13 ... These findings indicate that IL-1beta up-regulates Wnt-5A, and the activation of Wnt-5A signaling induces the expression of MMP-1 , MMP-3, MMP-9, and MMP-13 via the JNK signaling pathway in rabbit TMJ condylar chondrocytes