Levine et al., J Biol Chem 2007
(Calcium Signaling) :
Finally, siRNA mediated knockdown of caveolin-1 significantly enhanced AMPK phosphorylation, suggesting that AMPK is negatively regulated by caveolin-1 Salani et al., FASEB J 2012
(Carcinoma, Non-Small-Cell Lung...) :
Since caveolin-1 (Cav-1) plays a role in AMPK activation and energy balance, we investigated whether Cav-1 could participate in metformin 's inhibitory effect on IGF1 signaling