◀ Back to IL1A
CEBPD — IL1A
Text-mined interactions from Literome
Désilets et al., Biochem Biophys Res Commun 2000
:
Gel shift and supershift assays showed a strong decrease in the
IL-1 induced C/EBPbeta and
C/EBPdelta containing complexes binding to the HaptoA C/EBP DNA binding site of the haptoglobin promoter, by NaBu and TSA
Svotelis et al., Biochem Biophys Res Commun 2005
:
C/EBP delta regulates several inflammatory response genes, such as haptoglobin, in the rat intestinal epithelial cell line IEC-6 in
response to
IL-1
Miyoshi et al., Clin Exp Nephrol 2007
(Glomerulonephritis) :
In the in vitro study,
IL-1beta increased
C/EBP-delta mRNA levels in NS siRNA transfected MCs ( 7.3-fold ), but no increase was evident in C/EBP-delta siRNA transfected MCs
Ali et al., Int J Biochem Cell Biol 2010
:
The
IL-1 mediated
induction of
C/EBPdelta expression was attenuated in the presence of pharmacological inhibitors against c-Jun N-terminal kinase (JNK) ( curcumin and SP600125 ), casein kinase 2 ( CK2 ) ( apigenin ) and nuclear factor-kappaB (NF-kappaB) ( NF-kappaB activation inhibitor ) ... RNA interference assays showed significant attenuation of the
IL-1 induced expression of
C/EBPdelta following knockdown of the p50 and p65 subunits of NF-kappaB ... Taken together, these results suggest a potentially crucial role for NF-kappaB in the
IL-1 induced expression of
C/EBPdelta , and thereby downstream APP genes regulated by this transcription factor