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IL1A — VIP
Text-mined interactions from Literome
Eskay et al., Endocrinology 1992
:
Stimulation of
VIP and substance P biosynthesis by forskolin was markedly
enhanced by
IL-1 alpha , while forskolin stimulation of enkephalin and neurotensin biosynthesis was unaffected
Persson et al., Biochem Biophys Res Commun 2005
:
Furthermore,
IL-1beta stimulated IL-6 promoter activity in the osteoblastic cell line MC3T3-E1 stably transfected with a human IL-6 promoter/luciferase construct, and both
VIP , and the related neuropeptide PACAP-38,
increased the effect of IL-1beta in a synergistic manner
Dallos et al., Neuropeptides 2006
(Inflammation) :
The aims of this study were a systematic investigation of the
effects of the neuropeptides substance P ( SP ), calcitonin gene related peptide (CGRP),
vasoactive intestinal polypeptide (VIP) and galanin (GAL) on the inflammatory cytokine production (
IL-1alpha , IL-8 and TNF-alpha ) of the keratinocytes, and a study of their role in the production and secretion of nerve growth factor (NGF) and its precursor molecule ( proNGF )
Kelleher et al., J Immunol 1991
:
Our results demonstrated that
vasoactive intestinal peptide , the beta-adrenergic agonist, isoproterenol, PGE2,
IL-1 alpha , IL-1 beta, and TNF-alpha significantly
increased media SC levels in control or androgen containing cell cultures
Wang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2007
:
VIP could
regulate the expression pattern of
IL-1 , IL-6, TGF-beta and FasL by Leydig cells, which may contribute to maintain immune privilege of the testis
Spangelo et al., Endocrinology 1991
:
In the presence of
VIP and PGE2,
IL-1 alpha and IL-1 beta
increased IL-6 release without any apparent further change in extracellular or intracellular cAMP
Brenneman et al., Int J Dev Neurosci 1995
:
These data indicate that
VIP produced an
increase in the secretion of
IL-1 alpha while depleting IL-1 alpha mRNA
Lieb et al., J Neuroimmunol 1996
:
We demonstrate that the neuropeptides SP,
vasoactive intestinal peptide , substance K. cholecytokinine, alpha-endorphin and beta-endorphin are consistently unable to
induce the synthesis of
IL-1 and IL-6 in human peripheral blood monocytes