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CSF2 — SLPI
Text-mined interactions from Literome
Baranova et al., Int J Hematol 1999
(Neutropenia...) :
As described in studies on the
effect of
rhG-CSF on
ALP activity in healthy individuals, ALP activity was higher in SCN patients already on treatment with rhG-CSF
Yamaoka et al., Rinsho Byori 1992
(Leukemia, Promyelocytic, Acute) :
rhG-CSF induced a small but significant increase of NBT reducing ability and
ALP activity of the HL-60 cells ... Among various inducers of cell differentiation, 1,25 ( OH ) 2D3 and dimethylsulfoxide ( DMSO ) caused the increase of the NBT reducing ability and the suppression of
ALP activity
induced by
rhG-CSF , while RA enhanced both of them
Taoka et al., Leuk Res 1993
(Leukemia, Promyelocytic, Acute) :
Recombinant human granulocyte
colony stimulating factor ( rhG-CSF ) not only enhanced the growth of HL-60 cells, but also significantly
increased NBT reducing ability and
alkaline phosphatase (ALP) activity of the cells, which were enhanced by the treatment with retinoic acid ( RA ) ... This study suggests that RA and
rhG-CSF are the potent
inducers of
ALP activity of HL-60 cells and protein kinase C is supposed to have a role in this induction of ALP
Tsuruta et al., Br J Haematol 1996
(Leukemia, Myeloid...) :
With stimulation, the
ALP mRNA expression in both fractions was strongly enhanced by G-CSF, but the expression was
inhibited by
GM-CSF and/or IL-3