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ALB — INS

Text-mined interactions from Literome

Crane et al., J Cell Biol 1977 : The effects of insulin , cortisol, and epinephrine on general protein synthesis, and specifically on fibrinogen and albumin synthesis, have been tested on cells from both normal rats and adrenalectomized rats ... Insulin enhances albumin and general protein synthesis but has little effect on fibrinogen synthesis
Berrio et al., Horm Res 1992 : Due to the inhibitory and enhancing effects of albumin on the insulin activity of cinnamon and Brewer 's yeast, respectively, it is suggested that the effects of albumin be assessed when evaluating the insulin enhancing effects of other substances using isolated adipocytes
Messina et al., Biochim Biophys Acta 1992 (Liver Neoplasms, Experimental) : Rapid regulation of albumin transcription by insulin and phorbol esters in rat hepatoma cells ... The short-term effects of insulin and phorbol esters on the regulation of the albumin gene in rat H4IIE ( H4 ) hepatoma cells were investigated and compared to the expression of a gene known to be inhibited by these agents, phosphoenol pyruvate carboxykinase ( PEPCK ) ... Both insulin and phorbol esters inhibited transcription of the albumin gene in a rapid, dose dependent manner ... The ability of both phorbol esters and insulin to inhibit albumin transcription suggests that the negative control of this gene is a stable feature in H4 cells
Woo et al., Int J Cardiol 1992 (Albuminuria...) : Multivariate analysis showed that only systolic blood pressure and fasting glucose in men, and diastolic blood pressure and fasting insulin in women, independently contributed to urinary albumin : creatinine
Hilsted et al., Diabetologia 1992 (Hypoglycemia) : During similar conditions insulin increased the transcapillary escape rate of albumin and reduced plasma volume
Burke et al., J Cell Physiol 2006 : In transdifferentiated hepatocytes albumin was secreted, insulin stimulated lipid deposition and ciprofibrate enhanced the expression of catalase
Tessari et al., Diabetes Care 2006 (Diabetes Mellitus, Type 2...) : Insulin stimulates albumin synthesis but inhibits that of fibrinogen in both type 1 diabetic and healthy subjects ... In normoalbuminuric type 2 diabetic patients, postabsorptive albumin synthesis and its response to insulin were normal, whereas fibrinogen synthesis was increased, irrespective of metabolic control
Uchida et al., Atherosclerosis 1991 : Insulin stimulated the production of albumin , but inhibited the production of apo A-IV dose-dependently
De Feo et al., J Clin Invest 1991 (Diabetes Mellitus, Type 1) : Differential effects of insulin deficiency on albumin and fibrinogen synthesis in humans
Møller et al., Pharmacol Toxicol 1991 : The indicated increased clearance rate of plasma Phe after albumin may be caused by the significant increase of insulin , on which aspartame had no effect
Decaux et al., J Biol Chem 1991 : Transcription of the albumin gene, investigated by run-on assay, is active in the presence of insulin alone, with or without glucose, whereas transcription of the aldolase B gene is stimulated by glucose and insulin together, but not by insulin or glucose alone
Masumoto et al., Atherosclerosis 1988 : Insulin stimulated the production of albumin at concentrations over 10 ( -10 ) M, but inhibited the production of apo A-I at concentrations over 10 ( -8 ) M. Dexamethasone showed no significant effects on albumin production but stimulated apo A-I production at concentrations over 10 ( -6 ) M. Glucagon inhibited the production of albumin and apo A-I dose-dependently at concentrations over 10 ( -10 ) M
Ng et al., Br J Nutr 1988 : 5. In conclusion, NEFA, when raised to pathological levels, can inhibit the leucocyte Na-pump in vivo even in the presence of physiological levels of serum albumin , and may increase insulin secretion
Lloyd et al., Am J Physiol 1987 : Stimulation of albumin gene transcription by insulin in primary cultures of rat hepatocytes ... The second goal was to use the single stranded DNA probes to investigate the mechanism of the insulin mediated stimulation of albumin synthesis in primary cultures of rat hepatocytes ... Taken together, these findings demonstrate that insulin regulates synthesis of albumin at the level of gene transcription
Hutson et al., Am J Physiol 1987 : When added singly, either insulin or dexamethasone increased rates of albumin secretion in a dose dependent manner, but both hormones and an adequate supply of amino acids were necessary for maximal rates of secretion as well as long-term maintenance of the hepatocytes ( greater than 3-4 days )
Nawa et al., J Biol Chem 1986 : Insulin and triiodothyronine had no effect on transcription of the albumin gene
Drake et al., Biochem Biophys Res Commun 1985 : Insulin mediates the asynchronous accumulation of hepatic albumin and malic enzyme messenger RNAs
Flaim et al., Am J Physiol 1985 : Direct effect of insulin on albumin gene expression in primary cultures of rat hepatocytes ... The purpose of this study was to identify a cell culture system in which the role of insulin in regulating albumin gene expression could be investigated ... Furthermore, albumin secretion relative to the rate of total protein synthesis was reduced by approximately 50 % as a result of insulin deficiency
Crane et al., Mol Cell Biochem 1983 (Liver Neoplasms, Experimental) : Cortisol stimulates the synthesis of fibrinogen and other acute-phase proteins ; whereas, insulin stimulates albumin synthesis
Freidenberg et al., J Clin Endocrinol Metab 1983 (Hemolysis) : Furthermore, 5 % albumin , 2.5 mM N-ethylmaleimide, or excess unlabeled insulin ( 100 micrograms/ml ) inhibited insulin degradation ( even in the presence of hemolysis ) and prevented the rise in insulin binding
Patsch et al., J Clin Invest 1983 : Levels of apo-C-III3 and albumin were not affected by insulin
Lindsay et al., J Hum Hypertens 1995 (Albuminuria...) : We have examined diurnal BP variation in 25 microalbuminuric ( MA ) and 19 normoalbuminuric ( NMA ) patients with non-insulin dependent diabetes and related albumin excretion rate (AER) to diurnal BP variation in the microalbuminuric group
Sultan et al., Diabetes Res 1994 (Diabetes Mellitus, Experimental) : Insulin at physiological and non-physiological concentrations in the presence of albumin affects the metabolism of D-3-HB ; the stimulations of D-3-HB utilization averaged 32 % and 46 % in hearts from normal and diabetic rats respectively
Messina et al., Endocrinology 1994 : Insulin and phorbol 12-myristate 13-acetate ( PMA ) rapidly inhibit transcription of the tyrosine aminotransferase and albumin genes
Christensen et al., International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1993 (Hypertension) : Insulin decreased plasma volume and increased the fractional escape rate of albumin from plasma
Dahn et al., Metabolism 1994 : A notable aspect of the findings is that the albumin effects are insulin or glucose substrate dependent, which may have implications regarding liver function during nutritional support in critical illness
De Feo et al., Diabetes 1993 : The positive effect of insulin on albumin synthesis may play an important anabolic role during nutrient absorption by promoting the capture of a relevant amount of dietary essential amino acids into the protein, whereas the negative effect of insulin on fibrinogen synthesis might, at least partially, account for the increased plasma fibrinogen concentrations previously reported in poorly controlled diabetic patients