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FGF2 — INS

Text-mined interactions from Literome

Civil et al., Exp Eye Res 2000 (Cataract) : The accumulation of alphaB- and betaA3/1-crystallin was not affected by insulin in the presence of FGF-2
Hiriart et al., Isr Med Assoc J 2001 : Moreover, both NGF and FGF enhance glucose induced insulin secretion
Wang et al., Cell Transplant 2001 : Effect of basic fibroblast growth factor on insulin secretion from microencapsulated pancreatic islets : an in vitro study
Wang et al., J Biol Chem 2006 (Neoplasms...) : Although mitogenic vascular endothelial growth factor, transforming growth factor-beta1, and the anti-angiogenic endostatin levels in either serum or carcinoma tissue extracts did not change in cathepsin S- or cystatin C-null mice, tumor tissue basic fibroblast growth factor and serum type 1 insulin growth factor levels were higher in cystatin C-null mice, and serum type 1 insulin growth factor levels were also increased in cathepsin S-null mice
Layton et al., Molecular vision 2006 (Diabetes Mellitus, Experimental) : Insulin produced a dose dependent increase in FGF-2 in RPE cells and decrease in GFAP in Müller cells grown in 15 mM glucose ... It is suggested that decreased systemic insulin and high glucose levels contribute to decreased FGF-2 production in the RPE and increased glial cell activation in the diabetic retina
Wente et al., Diabetes 2006 (Diabetes Mellitus, Type 2...) : In islets isolated from diabetic rodents, FGF-21 treatment increased islet insulin content and glucose induced insulin secretion
Kharitonenkov et al., Endocrinology 2007 (Body Weight...) : When administered daily for 6 wk to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin , and glucagon
Izumiya et al., FEBS Lett 2008 : In cultured skeletal muscle cells, FGF21 expression and secretion was regulated by insulin , Akt transduction and LY294002
Xu et al., Am J Physiol Endocrinol Metab 2009 (Insulin Resistance...) : In ob/ob mice, FGF21 led to a 40-60 % decrease in blood glucose, insulin , and amylin levels within 1 h after injection, and the maximal effects were sustained for more than 6 h despite the 1- to 2-h half-life of FGF21 ... In DIO mice, FGF21 reduced fasting blood glucose and insulin levels and improved glucose tolerance and insulin sensitivity within 3 h of treatment
Vidaltamayo et al., Endocrine 1996 : We studied the effects of nerve growth factor (NGF), fibroblast growth factor ( FGF ) , and dibutyryl-cAMP ( dbcAMP ) on rat pancreatic ß-cell morphology and of NGF and dbcAMP on insulin secretion
Hamilton et al., J Cell Physiol 1985 : Their induction is, however, correlated with the ability of the polypeptide growth factor to stimulate DNA synthesis ; EGF, FGF , and serum induce the SIPs, whereas insulin does not, and insulin alone weakly stimulates DNA synthesis in these cells
Sadovnikova et al., Biull Eksp Biol Med 1988 : The effects of fibroblast growth factor ( FGF ) and nerve growth factor (NGF) on DNA synthesis and insulin secretion were studied in 4-5-day cultures of the isolated neonatal rat islets
Takeyama et al., FEBS Lett 1985 (Colonic Neoplasms) : In Swiss 3T3 cells, colon tumor promoting deoxycholate ( DOC ) enhanced DNA synthesis which was induced by fibroblast growth factor ( FGF ) in the presence of insulin ... In contrast to these bile acids, 12-O-tetradecanoylphorbol-13-acetate ( TPA ) induced DNA synthesis fully without FGF in the presence of insulin ... In these cells, FGF still induced DNA synthesis in the presence of insulin , but the maximal level was reduced to about one third of that in the control cells
Ueno et al., Nihon Eiseigaku Zasshi 1994 (Neovascularization, Pathologic) : However, neither NE nor insulin stimulated the expression of the bFGF gene in BCEC
Yamashita et al., Eur J Cell Biol 1995 (Hyperplasia) : Insulin stimulates the expression of basic fibroblast growth factor in rat brown adipocyte primary culture
Santa-Olalla et al., J Neurosci Res 1995 : The colony forming activity of bFGF was dependent on insulin , but bFGF and insulin cooperation was indirect since we could not observe colony formation in subcultures of cells derived from colonies, even in the presence of insulin
Imamura et al., Hepatology 1996 : In the presence of serum and physiological concentration of insulin , FGF-C ( 1211 ) by itself induces as much as 55 % of hepatocytes in culture to proliferate and up to 88 % when used in combination with hepatocyte growth factor or epidermal growth factor