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INS — PTBP1

Text-mined interactions from Literome

Varma et al., J Am Coll Cardiol 2001 (Angina Pectoris...) : 4 ) Glucose and insulin , which increase high-energy phosphates during ischemia, reduced increased DCS by 50 % ( p < 0.001 )
Fred et al., Biochem Biophys Res Commun 2005 : The aim of this study was to further elucidate the role of the polypyrimidine tract binding protein ( PTB ) in the control of insulin mRNA stability ... To further test the hypothesis that PTB controls insulin gene expression, betaTC-6 cells were treated with a PTB-specific siRNA to modify the beta-cell content of PTB ... We conclude that expression of the PTB gene controls insulin production
Greene et al., Biochem Biophys Res Commun 2006 : The IRS-1 PH and PTB domains are essential for insulin stimulated IRS-1 Tyr phosphorylation and insulin signaling, while Ser/Thr phosphorylation of IRS-1 disrupts these signaling events
Fred et al., Curr Diabetes Rev 2006 (Diabetes Mellitus...) : The role of PTB in insulin mRNA stability control