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INS — SOD1
Text-mined interactions from Literome
Bertrand et al., J Biol Chem 1999
:
We also show that
insulin increased
manganese-superoxide dismutase ( Mn-SOD ) mRNA expression through NF-kappaB activation and that Mn-SOD contributed to insulin antiapoptotic signaling since expression of antisense Mn-SOD RNA decreased this process
Bukan et al., Methods Find Exp Clin Pharmacol 2004
(Body Weight...) :
These results demonstrate that the sulfonylurea glyburide is capable of exerting direct
insulin-like effect on heart
superoxide dismutase , catalase and glutathione peroxidase activities of diabetic rats in vivo
Kino et al., Diabetes 2005
(Acquired Immunodeficiency Syndrome...) :
Moreover, Vpr antagonized
insulin induced suppression of the mRNA expression of the glucose 6-phosphatase, manganese
superoxide dismutase , and sterol carrier protein 2 genes, which are known targets of insulin and FOXO, in HepG2 cells
Narai et al., J Neurosci Res 2005
:
The
role of
insulin-like growth factor-1 (IGF-1) in
amyotrophic lateral sclerosis (ALS) and its mechanism of action are important from both pathogenic and therapeutic points of view
Akamine et al., J Vasc Res 2006
(Diabetes Mellitus, Experimental) :
However,
insulin increased
SOD activity but not its expression
Wang et al., Antioxid Redox Signal 2011
:
Whereas the three knockout groups displayed decreased plasma insulin concentrations and islet ß-cells mass, only
SOD1 ( -/- ) showed decreased body weight, increased blood glucose, and
blocked glucose stimulated
insulin secretion
Deepa et al., J Neural Transm 2011
(Amyotrophic Lateral Sclerosis) :
The present study was aimed to investigate if the
ALS-CSF affected the expression of trophic factors namely, brain derived neurotrophic factor (BDNF), fibroblast growth factor 2 (FGF2) and
insulin-like growth factor 1 (IGF1) in the newborn rat spinal cords
Komov et al., Radiobiologiia 1986
(Radiation Injuries, Experimental) :
[
Effect of
insulin and glucagon on
superoxide dismutase degradation in the liver of irradiated rats ] ... A study was made of the
effect of
insulin and glucagon on the time of functioning and degradation of
superoxidedismutase in the liver of rats irradiated with a dose of 8 Gy
Scharf et al., Hepatology 1996
:
It can be concluded that biosynthesis of individual IGFBPs and of
ALS are compartmentalized in adult rat liver and are distinctly
regulated by
insulin , IGF-I, and GH
Bereket et al., Clin Endocrinol (Oxf) 1996
(Acute Disease...) :
Insulin may
regulate circulating
ALS levels in catabolic states and helps to restore the IGF system
Scharf et al., Prog Growth Factor Res 1995
:
Insulin stimulated both the expression of
ALS and IGFBP-3 in co-cultures in a dose dependent manner, while expression of IGFBP-I was decreased