Gene interactions and pathways from curated databases and text-mining

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INS — SOD1

Text-mined interactions from Literome

Bertrand et al., J Biol Chem 1999 : We also show that insulin increased manganese-superoxide dismutase ( Mn-SOD ) mRNA expression through NF-kappaB activation and that Mn-SOD contributed to insulin antiapoptotic signaling since expression of antisense Mn-SOD RNA decreased this process
Bukan et al., Methods Find Exp Clin Pharmacol 2004 (Body Weight...) : These results demonstrate that the sulfonylurea glyburide is capable of exerting direct insulin-like effect on heart superoxide dismutase , catalase and glutathione peroxidase activities of diabetic rats in vivo
Kino et al., Diabetes 2005 (Acquired Immunodeficiency Syndrome...) : Moreover, Vpr antagonized insulin induced suppression of the mRNA expression of the glucose 6-phosphatase, manganese superoxide dismutase , and sterol carrier protein 2 genes, which are known targets of insulin and FOXO, in HepG2 cells
Narai et al., J Neurosci Res 2005 : The role of insulin-like growth factor-1 (IGF-1) in amyotrophic lateral sclerosis (ALS) and its mechanism of action are important from both pathogenic and therapeutic points of view
Akamine et al., J Vasc Res 2006 (Diabetes Mellitus, Experimental) : However, insulin increased SOD activity but not its expression
Wang et al., Antioxid Redox Signal 2011 : Whereas the three knockout groups displayed decreased plasma insulin concentrations and islet ß-cells mass, only SOD1 ( -/- ) showed decreased body weight, increased blood glucose, and blocked glucose stimulated insulin secretion
Deepa et al., J Neural Transm 2011 (Amyotrophic Lateral Sclerosis) : The present study was aimed to investigate if the ALS-CSF affected the expression of trophic factors namely, brain derived neurotrophic factor (BDNF), fibroblast growth factor 2 (FGF2) and insulin-like growth factor 1 (IGF1) in the newborn rat spinal cords
Komov et al., Radiobiologiia 1986 (Radiation Injuries, Experimental) : [ Effect of insulin and glucagon on superoxide dismutase degradation in the liver of irradiated rats ] ... A study was made of the effect of insulin and glucagon on the time of functioning and degradation of superoxidedismutase in the liver of rats irradiated with a dose of 8 Gy
Scharf et al., Hepatology 1996 : It can be concluded that biosynthesis of individual IGFBPs and of ALS are compartmentalized in adult rat liver and are distinctly regulated by insulin , IGF-I, and GH
Bereket et al., Clin Endocrinol (Oxf) 1996 (Acute Disease...) : Insulin may regulate circulating ALS levels in catabolic states and helps to restore the IGF system
Scharf et al., Prog Growth Factor Res 1995 : Insulin stimulated both the expression of ALS and IGFBP-3 in co-cultures in a dose dependent manner, while expression of IGFBP-I was decreased