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IL23A — IRF6

Text-mined interactions from Literome

Ma et al., Cell Biol Int 2004 : IL-23 p19 and IL-12 p35 mRNAs were expressed in fresh PBMC, and expression of all IL-23 and IL-12 subunits was up-regulated by LPS and SAC ... LPS induced increase of IL-23 and IL-12 subunits expression was CD14 dependent, while CD14 was not involved in SAC induced p19 transcription
Xu et al., J Immunol 2007 (Encephalomyelitis, Autoimmune, Experimental) : In primary astrocytes, LPS induced the production of IL-12p40, IL-23 , and IL-27p28 proteins
Siegemund et al., Immunobiology 2007 : Stimulation of BMDC and BMMPhi with S. enterica serovar Enteritidis ( SE ) or LPS resulted in the release of IL-12 and IL-23 by BMDC but not by BMMPhi
Goyarts et al., Exp Dermatol 2008 : Furthermore, forskolin also inhibited the LPS induced levels of TNF-alpha, IL-12 p40, IL-23 p19 and IL-6, supporting the hypothesis that the effects of NE are mediated by cAMP
Mühlbauer et al., J Biol Chem 2008 : In this study, we investigated the role of Bcl3 in controlling LPS induced IL-23p19 gene expression in bone marrow derived dendritic cells ( BMDC ) isolated from IL-10 ( -/- ) mice ... Bcl3 overexpression decreased LPS induced IL-23p19 gene expression in IL-10 ( -/- ) BMDC, which correlated with enhanced NF-kappaB p50 binding and decreased RelA binding to the gene promoter ... Conversely, Bcl3 knockdown enhanced LPS induced IL-23p19 gene expression in WT BMDC ... Moreover, LPS induced IL-23p19 gene expression was significantly enhanced in Bcl3 ( -/- ) BMDC compared with WT BMDC
Aldhous et al., Inflamm Bowel Dis 2008 (Colitis, Ulcerative...) : Stimulation by LPS and PHA ( 5 microg/mL ) increased IL12/IL23p40 production from CD and UC versus HC ( P < 0.05 ) ; PHA ( 0.5 microg/mL ) increased IL1beta in UC and decreased TGFbeta from CD and UC ( P < 0.01 )
Martins et al., Inflamm Bowel Dis 2009 (Inflammatory Bowel Diseases) : Intestinal tissue samples isolated from G-CSF receptor-deficient mice constitutively expressed higher levels of TNFalpha, IL-23, and IL-12 than those from wildtype mice, and pretreatment of G-CSF suppressed lipopolysaccharide (LPS) induced IL-23 in human peripheral blood mononuclear cells
Abe et al., Clin Exp Immunol 2009 : LPS-ICs also enhanced TNF-alpha and IL-6 secretion, but suppressed IL-23 secretion
Liu et al., J Biol Chem 2009 (Autoimmune Diseases...) : We demonstrate that induction of IL-23 p19 gene expression by LPS depends on the TLR4 and MyD88 pathways
Louis et al., J Leukoc Biol 2010 (HIV Infections) : IL-23 production, measured by ELISA after PBMC stimulation, was induced by LPS in strong correlation with VLs. IL-12p70 production required the addition of IFN-gamma and was transiently increased in patients compared with controls in correlation with VLs, whereas IL-23 was increased sustainedly
Sheikh et al., J Immunol 2010 (Colitis...) : IFN-gamma attenuates LPS mediated IL-23 expression in murine macrophages
Kakimoto et al., J Physiol Biochem 2010 : The decreased IL-23 production in Cot/Tpl2 ( -/- ) macrophages is, at least partly, regulated at the transcriptional level, as the LPS mediated IL-23 p19 mRNA induction was significantly less in Cot/Tpl2 ( -/- ) macrophages
Sheikh et al., J Biol Chem 2011 (Chronic Disease...) : This ISRE mediated, in part, Il23a promoter induction by LPS and inhibition of LPS induced activity by IFN-? ... Functionally, IRF-1 is a negative regulator of Il23a in LPS stimulated BMMs. IRF-1 ( -/- ) BMMs demonstrated enhanced LPS induced Il23a expression compared with WT BMMs
Peters et al., J Immunol 2011 : Incubation of bone marrow derived dendritic cells with THP treated fibroblasts enhanced sterile IL-6 production and LPS induced generation of IL-1ß, IL-12, IL-23 , and TNF-a ... Finally, there is a strong synergy between calcium depletion in the ER and sterile IL-6, as well as LPS dependent IL-1ß, IL-12, IL-23 , and TNF-a innate responses, findings that have implications for understanding inflammatory diseases that originate in the ER
Song et al., BMC complementary and alternative medicine 2011 (Colitis...) : LPS induced IL-12p40, IL-23p19 , IL-6 and IL-1ß mRNA expressions were inhibited by BTE
Zeng et al., Arthritis Rheum 2011 (Spondylitis, Ankylosing) : The greater production of IL-23 by AS patient macrophages in response to LPS provides further support for the development of Th17/IL-23 directed therapy
Bosmann et al., Shock 2013 (Acute Lung Injury) : Activation of these macrophages by LPS resulted in release of IL-23 in vitro
Orr et al., PLoS Pathog 2013 (Candidiasis...) : C. albicans- and LPS induced IL-12 and IL-23 production was blunted in Lat2 ( -/- ) DCs
Saito et al., Int Arch Allergy Immunol 2013 (Eosinophilic Granuloma...) : In addition, the percentages of monocytes and the percentages of mDCs that produced IL-27 and IL-23p19 in response to LPS stimulation were positively correlated with the percentages of Tr1 cells and Th17 cells in peripheral blood
Carrión et al., Neuroimmunomodulation 2013 : TNFa, LPS and poly ( I:C ) increased IL-12 and IL-23 levels in cells derived from patients presenting both pathologies