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IRF6 — SRC

Text-mined interactions from Literome

Napolitani et al., Eur J Immunol 2003 : We show that LPS induces activation of c-Src and Lyn in human DC
Severgnini et al., Am J Physiol Lung Cell Mol Physiol 2004 (Acute Disease...) : We also demonstrated that LPS activates both the STAT kinases, Src and JAK, in the lung with kinetics that are consistent with STAT activation
Leu et al., Mol Immunol 2006 (Endotoxemia...) : And this LPS mediated c-Src induction is also observed in macrophages recovered from LPS challenged rats
Hsu et al., Mol Pharmacol 2007 : In essence, GA decreased LPS induced Hsp90/pp60Src heterocomplex formation
Su et al., Clin Chim Acta 2006 : Src , Lyn and MAPKs are involved in LTA and LPS signaling in murine macrophages
Lee et al., J Immunol 2007 (Respiratory Distress Syndrome, Adult) : LPS resulted in c-Src phosphorylation in lung tissue and the phospho-c-Src was predominantly localized in recruited neutrophils and alveolar macrophages
Lin et al., Toxicol Appl Pharmacol 2008 : LPS stimulated Src , PYK2, EGFR, and Akt phosphorylation and VCAM-1 expression were attenuated by the inhibitors of Src ( PP1 ), EGFR ( AG1478 ), PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), respectively, or transfection with siRNAs of Src or Akt and shRNA of p110
Lee et al., Br J Pharmacol 2008 (Disease Models, Animal...) : In particular, davallialactone strongly inhibited the LPS induced phosphorylation and kinase activity of Src , implying that Src may be a potential pharmacological target of davallialactone
Liu et al., J Biol Chem 2012 : LPS increased binding of both c-Src and Fyn to GST-TRAF6 but not to a GST-TRAF6 mutant in which the three prolines in the putative Src homology 3 domain binding motif ( amino acids 461-469 ) were substituted with alanines ... Finally, LPS increased binding of activated Tyr ( P ) ( 416 ) -SFK to GST-TRAF6, and preincubation of HMVEC-Ls with SFK-selective tyrosine kinase inhibitors, PP2 and SU6656, diminished TRAF6 binding to c-Src and Fyn
McElroy et al., PloS one 2012 : LPS induction of COX-2 requires Src-family kinase signaling while LPS transactivation of EGFR requires matrix metalloprotease ( MMP ) activity
Lee et al., Cell communication and signaling : CCS 2012 : We observed that LPS induced TLR4, MyD88, c-Src , and p47phox complex formation determined by co-immunoprecipitation and Western blot