Gene interactions and pathways from curated databases and text-mining

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BCL3 — IL8

Text-mined interactions from Literome

Cassatella et al., Eur J Immunol 2005 : In this study, we show that modulation by IL-10 of LPS induced TNF-alpha, CXCL8/IL-8 and IL-1 receptor antagonist (IL-1ra) mRNA accumulation in neutrophils already expressing a functional IL-10R and antigenic SOCS-3 ( i.e. in `` 4-h cultured '' neutrophils ) occurs with kinetics that are similar to those observed in `` time 0 '' neutrophils, depends on de novo protein synthesis, but does not require SOCS-1, SOCS-3, heme oxygenase and Bcl-3 induction
Jamaluddin et al., J Virol 2005 : Transient expression of Bcl-3 potently inhibited virus-inducible IL-8 transcription by disrupting both the NF-kappaB and STAT/IRF pathways
Brocke-Heidrich et al., Oncogene 2006 (Multiple Myeloma) : In this study, interleukin (IL)-6 induced BCL3 expression and its effect on survival of multiple myeloma ( MM ) cells were examined
Zhou et al., Hepatobiliary Pancreat Dis Int 2013 (Adenocarcinoma...) : The purpose of this study was to investigate the roles of the pro-apoptotic TRAIL receptors, TRAIL-R1 and TRAIL-R2, as well as Bcl-xL and TRAF2 in TRAIL induced expression of the pro-inflammatory cytokine IL-8 and the invasion promoting protein urokinase ( uPA ) in pancreatic ductal adenocarcinoma ( PDAC ) cells ... Overexpression of TRAF2 or Bcl-xL strongly increased TRAIL mediated upregulation of uPA and IL-8