Murakami et al., J Biol Chem 2004
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By contrast, SOX2 was a poor activator of Fgf-3 transcription, and when Sox2 was coexpressed with Gata4, it negatively modulated the strong activation mediated by GATA-4
Abelló et al., Dev Biol 2010
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Independent regulation of Sox3 and Lmx1b by FGF and BMP signaling influences the neurogenic and non-neurogenic domains in the chick otic placode
Pearson et al., Development 2011
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We show that collar cells are composed of Fgf3 ( + ) SOX3 ( + ) proliferating progenitors, the induction of which is SHH dependent, but the maintenance of which requires FGF signalling