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NTF3 — PTPN11

Pathways - manually collected, often from reviews:

• NCI Pathway Database SHP2 signaling: SHP2 (PTPN11) → NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) (modification, collaborate)
  Dixon et al., Biochim Biophys Acta 2006, Hadari et al., Mol Cell Biol 1998
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database SHP2 signaling: NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) → FRS2 family/SHP2 complex (FRS3_FRS2-PTPN11) (modification, activates)
  Dixon et al., Biochim Biophys Acta 2006, Hadari et al., Mol Cell Biol 1998
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: SHP2 (PTPN11) → NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) (modification, collaborate)
  Dixon et al., Biochim Biophys Acta 2006, Hadari et al., Mol Cell Biol 1998
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) → FRS2 family/SHP2 complex (FRS3_FRS2-PTPN11) (modification, activates)
  Dixon et al., Biochim Biophys Acta 2006, Hadari et al., Mol Cell Biol 1998
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Neurotrophic factor-mediated Trk receptor signaling: NGF/NGFR-active (NTRK1/NGF/NTF3/NTRK3/BDNF/NTRK2/NTF4/NTRK2) → FRS2 family/SHP2 complex (FRS3_FRS2-PTPN11) (modification, activates)
  Kao et al., J Biol Chem 2001
  Evidence: physical interaction

Text-mined interactions from Literome

Ohnishi et al., J Neurochem 1999 : Furthermore, brain derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) also induced the tyrosine phosphorylation of BIT and the association with SHP-2 in primary cultured rat neurons
Araki et al., J Neurochem 2000 : Shp-2 , a Src homology 2 domain containing cytoplasmic tyrosine phosphatase, is involved in neurotrophin signaling in PC12 cells and cultured cerebral cortical neurons