Modugno et al., Oncogene 2002
(Neoplasm Metastasis...) :
Deletion analysis of the first intron localized an enhancer activity in the first 5 ' 214 bp that upregulates both 37LRP and SV40 promoter activity and is repressed by both wt and mutant p53 Xiong et al., Journal of the American Heart Association 2013
:
The activation of p66Shc but not p53 by Arg-II was dependent on extracellular signal regulated kinases ( ERKs ) and sequential activation of 40S ribosomal protein S6 kinase 1 (S6K1)-c-Jun N-terminal kinases (JNKs)