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PTGES — RELA
Text-mined interactions from Literome
Gómez-Hernández et al., Atherosclerosis 2006
(Carotid Artery Diseases) :
We have studied COX-2, mPGES-1 and PGE2 receptors ( EPs ) expression in peripheral blood mononuclear cells ( PBMC ) and atherosclerotic plaques of 29 patients with carotid stenosis as well as the
effect of different
nuclear factor-kappaB (NF-kappaB) inhibitors on COX-2,
mPGES-1 and EPs expression in cultured monocytic cells ( THP-1 ) ... In cytokine treated cultured THP-1, the
NF-kappaB inhibitors parthenolide, Bay 11-7082 and PDTC
reduced COX-2,
mPGES-1 and EP-1/EP-3/EP-4 expression as well as PGE2 levels
Ackerman et al., Biol Reprod 2008
:
We hypothesized that
NFkappaB might
regulate cytokine induced
PTGES expression in amnion cells ... In conclusion, our results support a
role for
NFkappaB in cytokine induced
PTGES expression in amnion mesenchymal cells in vitro
Frasor et al., Endocrinology 2008
:
Surprisingly, the combination of E2 and cytokines leads to a synergistic up-regulation of
PTGES in an ER and
nuclear factor-kappaB (NFkappaB) dependent manner
Barakat et al., Naunyn Schmiedebergs Arch Pharmacol 2009
(Brain Ischemia...) :
Expression of a constitutively active IkappaB kinase (IKK) or the
NF-kappaB subunit p65 in neurons
stimulated the transcription of cPLA-2, COX-2, and
mPGES-1