Gene interactions and pathways from curated databases and text-mining

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PTGES — RELA

Text-mined interactions from Literome

Gómez-Hernández et al., Atherosclerosis 2006 (Carotid Artery Diseases) : We have studied COX-2, mPGES-1 and PGE2 receptors ( EPs ) expression in peripheral blood mononuclear cells ( PBMC ) and atherosclerotic plaques of 29 patients with carotid stenosis as well as the effect of different nuclear factor-kappaB (NF-kappaB) inhibitors on COX-2, mPGES-1 and EPs expression in cultured monocytic cells ( THP-1 ) ... In cytokine treated cultured THP-1, the NF-kappaB inhibitors parthenolide, Bay 11-7082 and PDTC reduced COX-2, mPGES-1 and EP-1/EP-3/EP-4 expression as well as PGE2 levels
Ackerman et al., Biol Reprod 2008 : We hypothesized that NFkappaB might regulate cytokine induced PTGES expression in amnion cells ... In conclusion, our results support a role for NFkappaB in cytokine induced PTGES expression in amnion mesenchymal cells in vitro
Frasor et al., Endocrinology 2008 : Surprisingly, the combination of E2 and cytokines leads to a synergistic up-regulation of PTGES in an ER and nuclear factor-kappaB (NFkappaB) dependent manner
Barakat et al., Naunyn Schmiedebergs Arch Pharmacol 2009 (Brain Ischemia...) : Expression of a constitutively active IkappaB kinase (IKK) or the NF-kappaB subunit p65 in neurons stimulated the transcription of cPLA-2, COX-2, and mPGES-1