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PTGS2 — TAB1

Text-mined interactions from Literome

Choi et al., J Environ Pathol Toxicol Oncol 2005 : NF-kB inducing kinase (NIK) and TGF-k activated kinase 1 (TAK1) , the upstream signaling molecules of NF-kB, are involved in the silica mediated COX-2 expression
Neil et al., Cancer Res 2008 (Disease Progression) : TAB1 ( 411 ) expression also inhibited TGF-beta stimulated tumor necrosis factor-alpha and cyclooxygenase-2 expression in 4T1 cells
Ridder et al., J Exp Med 2011 (Fever...) : In conclusion, we demonstrate that TAK1 in brain endothelial cells induces COX-2 , most likely by activating p38 MAPK and c-Jun, and is necessary for fever and sickness behavior