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KHSRP — RHOA
Text-mined interactions from Literome
Yamashita et al., Nat Neurosci 2003
:
Here we show that direct interaction of the Rho GDP dissociation inhibitor (Rho-GDI) with
p75 ( NTR )
initiates the activation of
RhoA , and this interaction between p75 ( NTR ) and Rho-GDI is strengthened by MAG or Nogo
Harrington et al., J Biol Chem 2008
:
Here, we report that Kalirin9, a dual RhoGEF, binds p75 directly and regulates
p75-Nogo receptor dependent
RhoA activation and neurite inhibition in response to myelin associated glycoprotein
Uesugi et al., Cell death & disease 2013
(Optic Nerve Injuries) :
Although no direct interaction of p75NTR with ephrin-B3 was observed, Pep5, a peptide that specifically inhibits
RhoA activation
mediated by
p75NTR , reduced the effect of ephrin-B3