Gene interactions and pathways from curated databases and text-mining

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KHSRP — RHOA

Text-mined interactions from Literome

Yamashita et al., Nat Neurosci 2003 : Here we show that direct interaction of the Rho GDP dissociation inhibitor (Rho-GDI) with p75 ( NTR ) initiates the activation of RhoA , and this interaction between p75 ( NTR ) and Rho-GDI is strengthened by MAG or Nogo
Harrington et al., J Biol Chem 2008 : Here, we report that Kalirin9, a dual RhoGEF, binds p75 directly and regulates p75-Nogo receptor dependent RhoA activation and neurite inhibition in response to myelin associated glycoprotein
Uesugi et al., Cell death & disease 2013 (Optic Nerve Injuries) : Although no direct interaction of p75NTR with ephrin-B3 was observed, Pep5, a peptide that specifically inhibits RhoA activation mediated by p75NTR , reduced the effect of ephrin-B3