Gene interactions and pathways from curated databases and text-mining

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CXCL5 — IRF6

Text-mined interactions from Literome

Si et al., J Immunol 2004 (Acquired Immunodeficiency Syndrome) : Interestingly, although LPS induced IL-8/CXCL8 was dependent on NF-kappaB, the baseline or 15d-PGJ ( 2 ) -mediated IL-8/CXCL8 production was NF-kappaB independent
Jeyaseelan et al., Am J Respir Cell Mol Biol 2005 (Pneumonia) : The aims of the present study were to identify the cellular origin of CXCL5 and to determine the signaling cascades that regulate its expression in the lung during LPS induced inflammation and in isolated LPS stimulated CXCL5 expressing cells ... Similarly, TLR4, and p38 and c-Jun N-terminal kinases, are associated with LPS induced CXCL5 expression in AEII cells
Dürk et al., Int Immunol 2005 : Pharmacological studies with isotype-selective receptor agonists allowed us to show that 5-HTR(3) subtype up-regulates the LPS induced production of IL-1beta, IL-6 and IL-8/CXCL8 , while it was not involved in TNF-alpha and IL-12p40 secretion
Cassatella et al., Eur J Immunol 2005 : In this study, we show that modulation by IL-10 of LPS induced TNF-alpha, CXCL8/IL-8 and IL-1 receptor antagonist (IL-1ra) mRNA accumulation in neutrophils already expressing a functional IL-10R and antigenic SOCS-3 ( i.e. in `` 4-h cultured '' neutrophils ) occurs with kinetics that are similar to those observed in `` time 0 '' neutrophils, depends on de novo protein synthesis, but does not require SOCS-1, SOCS-3, heme oxygenase and Bcl-3 induction
Hasan et al., BMC immunology 2005 (Tuberculosis...) : BCG-, and LPS induced CXCL8 secretion was comparable between patients and controls
Wehrwein et al., Cardiovascular diabetology 2006 (Diabetes Mellitus, Type 1) : Monocytes were isolated from controls and T1D patients and the LPS stimulated increase of IL-6, CXCL8 , monocyte chemotactic protein 1 ( CCL2, MCP-1 ) and superoxide dismutase ( SOD 2 ), as well as the LPS mediated decrease of apolipoprotein E (Apo E) in primary human monocytes from controls and T1D patients was determined
De Plaen et al., Immunology 2006 : In conclusion, CXCL2 gene is expressed in enterocytes in response to both TNF and LPS
Carvalho et al., Inflammopharmacology 2006 (Disease Models, Animal...) : In vitro data revealed that U. guianensis impaired LPS induced nitric oxide and CXCL8 generation by murine peritoneal macrophages, as well as OVA induced interleukin-5 synthesis by previously sensitized spleen cells
Pioli et al., J Immunol 2007 : In this study, we demonstrate that 17beta-estradiol ( E2 ) attenuates LPS induced expression of CXCL8 in human peripheral blood monocytes
Tamassia et al., Int Immunol 2008 (Sepsis...) : Consistent with the presence of a fully functional IL-10R, modulation of LPS induced CXCL8 , CCL4, tumour necrosis factor-alpha and IL-1ra gene expression was also rapidly induced by IL-10 in septic, but not normal, neutrophils
Anand et al., J Immunol 2008 : In the present study, we determined the role of a nonreceptor proline-rich tyrosine kinase, Pyk2, in LPS induced IL-8 ( CXCL8 ) production in endothelial cells
Farkas et al., Scand J Immunol 2008 : LPS itself significantly augments CXCL-8 production and co-administration of MDP further increases cytokine secretion
Gouwy et al., J Leukoc Biol 2009 : Furthermore, LPS rapidly induced the expression of IL-8/CXCL8 but not of the CCL2 receptor CCR2 in monocytic cells
Hoth et al., J Trauma 2009 (Contusions...) : Injury + LPS showed immune priming observed by lung injury histology and increased bronchoalveolar lavage neutrophilia, lung myeloperoxidase and serum IL-6, CXCL1 , and MIP-2 levels when compared with injury + vehicle or LPS alone
Kim et al., Immune network 2009 : As a result of these properties, we examined the effect of 15d-PGJ ( 2 ) on the LPS induced IL-8/CXCL8 mRNA expression in VSMCs from SHR ... A NAD ( P ) H oxidase inhibitor inhibited the upregulatory effect of 15d-PGJ ( 2 ) on LPS induced IL-8/CXCL8 mRNA expression in SHR VSMCs, and an increase in NAD ( P ) H oxidase activity was detected in SHR VSMCs treated with 15d-PGJ ( 2 ) /LPS ... Our results indicate that the upregulatory effect of 15d-PGJ ( 2 ) on LPS induced IL-8/CXCL8 expression in SHR VSMCs is mediated through the PPARgamma and ERK pathway, and may be related to NAD ( P ) H oxidase activity ... However, p38 inactivation may also play an important role in 15d-PGJ ( 2 ) /LPS induced IL-8/CXCL8 expression in SHR VSMCs
Sheldon et al., PloS one 2010 (Cattle Diseases...) : Endometrial epithelial or stromal cells from wild type but not Toll-like receptor 4 (TLR4) null mice secreted prostaglandin E ( 2 ) and chemokine ( C-X-C motif ) ligand 1 ( CXCL1 ) in response to LPS from EnPEC, highlighting the key role of LPS in PID
Outtz et al., J Immunol 2010 (Inflammation) : Inhibition of Notch signaling decreased induction of the inflammatory cytokines IL-6, IL-12, CXCL10 , MCP-1, monokine induced by IFN-?, and TNF-a in macrophages in response to LPS/IFN-?
Sheldon et al., PloS one 2010 : Stromal and epithelial cells isolated from the endometrium of WT but not Tlr4 ( -/- ) mice, secreted IL-6, CXCL1 , CCL20 and prostaglandin E ( 2 ) in response to LPS , in a concentration and time dependent manner
Wendlandt et al., Innate Immun 2012 : When miR-200b or miR-200c mimics were transfected into the differentiated monocytic THP-1 cell line, the abundance of MyD88 transcripts, as well as LPS induced expression of the pro-inflammatory molecules IL-6, CXCL9 and TNF-a were diminished
Roos et al., Biochem Biophys Res Commun 2012 (Pneumonia) : We hypothesized that C/EBPß in the lung epithelium contributes to lipopolysaccharide (LPS) induced airway neutrophilia and expression of neutrophil chemoattractant chemokine ( C-X-C ) motif ligand ( CXCL)1, as well as the suppressive effects of long acting ß ( 2 ) -agonists ( LABAs ) and glucocorticoids (GCs)
Yamamoto et al., J Immunol 2012 (Pneumonia, Pneumococcal) : In response to LPS , only 2 of 84 cytokine transcripts ( CCL20 and CXCL5 ) were blunted in lungs of mutants, suggesting that a very limited subset of immune mediators is selectively elaborated by the alveolar epithelium
Plumb et al., PloS one 2013 : 17-BMP suppression of LPS induced TNFa, IL-6 and CXCL8 was measured by ELISA and GR phosphorylation was measured by immunohistochemistry and Western blot