Gene interactions and pathways from curated databases and text-mining

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CD8A — TLR2

Text-mined interactions from Literome

Mercier et al., J Immunol 2009 : Using altered peptide ligands, we demonstrate that TLR2 engagement increases CD8 T cell activation and enables the generation of functional memory cells in response to a low TCR signal
Geng et al., Cancer Res 2010 (Melanoma...) : In this study, we examined the antitumor activity and survival of TLR2-MyD88 stimulated CD8 T cells derived from melanoma patients and T-cell receptor transgenic pmel mice
Heidegger et al., J Immunol 2013 (Salmonella Infections) : We further show that this downregulation is dependent on TLR signaling, and that the TLR activated naive CD8 ( + ) T cells are blocked from entering GALT