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CD4 — CD83
Text-mined interactions from Literome
Munster et al., Int Immunol 2004
:
CD83 is a marker of dendritic cell ( DC ) differentiation/activation and its expression in the mouse thymus
contributes to
CD4 ( + ) T lymphocyte development
Kuwano et al., Int Immunol 2007
:
In mice,
CD83 expression by thymic stromal cells
regulates CD4 ( + ) T cell development, with CD83 ( -/- ) mice demonstrating dramatic reductions in both thymus and peripheral CD4 ( + ) T cells
Kretschmer et al., Immunol Lett 2008
:
CD83 expression levels did not significantly
affect CD4 ( + ) T cell activation in vivo, but a weak positive correlation of CD83 expression with CD4 ( + ) T cell activation was observed in vitro under suboptimal stimulation conditions
Su et al., J Immunol 2009
:
This study supports the novel mechanism of ubiquitination by GRAIL, identifies CD83 as a substrate of GRAIL, and ascribes a
role for
CD83 in
CD4 T cell activation
Chen et al., Hybridoma (Larchmt) 2011
:
CD83 , a maturation marker for human and mouse dendritic cells (DCs),
plays a critical role in
CD4 ( + ) T cell development as well as peripheral immune regulation