Gene interactions and pathways from curated databases and text-mining

◀ Back to IRF6

FPR2 — IRF6

Text-mined interactions from Literome

Le et al., J Immunol 2004 : Functional FPR2 was induced by bacterial LPS in murine microglial cells, the resident phagocytic cells that play a pivotal role in inflammatory and immunological diseases in the CNS ... These effects of TGF-beta1 culminate in the inhibition of LPS induced activation of NF-kappaB and the up-regulation of FPR2 in microglial cells
Mandal et al., J Immunol 2005 : In this study, we show that LPS can markedly enhance the expression of the formyl peptide receptor gene ( FPR1 ) in mouse macrophages and neutrophils by enhancing transcription and by stabilization of the mRNA