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IRF6 — UCN

Text-mined interactions from Literome

Kageyama et al., Endocrinology 1999 : As measured by ribonculease protection assay, lipopolysaccharide (LPS) induced a 2-fold time dependent increase in thymic Ucn mRNA levels within 6 h ... Ucn mRNA in thymus, but not spleen, was significantly increased after ACTH injection ; however, LPS did not increase Ucn expression in the thymus of adrenalectomized rats with corticosterone replacement, despite substantial increases in ACTH
Ikeda et al., J Mol Endocrinol 2009 (Inflammation) : Ucn I mRNA levels were shown to be up-regulated by lipopolysaccarides (LPS) , tumor necrosis factor-alpha (TNF-alpha), Ang II, H ( 2 ) O ( 2 ), and pyrrolidinedithiocarbamate ( PDTC ) ... In addition, the secretion of Ucn I from HL-1 cardiomyocytes was stimulated by LPS and TNF-alpha
Zhang et al., Br J Pharmacol 2009 : Ucn1 augmented LPS induced expression of COX-2 and ICAM-1 in RAECs in a time- and concentration dependent manner
Yuan et al., Am J Physiol Gastrointest Liver Physiol 2012 : LPS increased Ucn mRNA levels significantly in both mucosa and S+M, reaching a maximal response at 6 h postinjection and returning to basal levels at 24 h except for Ucn 1 in S+M
Wan et al., J Cell Physiol 2013 : Taken together, our data suggest that Ucn1 increase LPS induced endothelial permeability by disrupting the VE-cadherin-ß-catenin complex via activation of CRHR ( 2 ) and PKD-HSP27 signaling pathway
Wan et al., J Endocrinol 2013 : Conversely, in the presence of LPS , DHT augmented the LPS induced increase in UCN1 expression, which was, interestingly, not affected by flutamide