Gene interactions and pathways from curated databases and text-mining

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CD3D — IL15

Text-mined interactions from Literome

Matthys et al., Clin Exp Immunol 2002 : These data demonstrate that systemic IL-15 exerts anti-apoptotic activity on immature T cells and establish a regulatory mechanism whereby TCR/CD3 engagement induces IL-15 expression via an IFN-gamma dependent pathway
Mustelin et al., Science 1990 : At doses that inhibited TPK activity and tyrosine phosphorylation of the TCR zeta subunit, but not phospholipase C activity, genistein prevented TCR-CD3 mediated phospholipase C activation, interleukin-2 receptor expression, and T cell proliferation