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GATA1 — SETD2
Text-mined interactions from Literome
Yamashita et al., J Biol Chem 2001
:
The results support essential
roles for AP-1,
GATA-2 , and NF-1 in stabilizing the binding of
HIF-1 and promoting recruitment of p300/CBP to the ET-1 hypoxia response complex
Zhang et al., J Cell Mol Med 2012
:
In this study, we show that hypoxia induced
GATA1 expression is
mediated by
HIF1 in erythroid cells ... Enforced
HIF1a expression
increased GATA1 expression, while HIF1a knockdown by RNA interference decreased GATA1 expression ... These results suggested that
HIF1 mediated
GATA1 up-regulation promotes erythropoiesis in order to satisfy the needs of an organism under hypoxic conditions