Cassina et al., J Neurochem 2005
(Amyotrophic Lateral Sclerosis) :
FGF-1 induced accumulation of the FGF receptor 1 (FGFR1) in astrocyte nuclei and potently stimulated nerve growth factor (NGF) expression and secretion
Ono et al., Neurosci Lett 1991
:
Stimulation of biosynthesis of nerve growth factor by acidic fibroblast growth factor in cultured mouse astrocytes
Ji et al., Regul Pept 1996
:
Taken together, the present results suggest ( 1 ) that aFGF, bFGF and NGF differentially regulate neuropeptide expression in vivo ; ( 2 ) that FGFs can inhibit neuropeptide upregulation of some peptides after nerve injury ; and ( 3 ) that aFGF and NGF may induce pain related behavior
Rius et al., FEBS Lett 1997
(Pheochromocytoma) :
Sphingosine kinase activity induced by NGF , but not FGF , was blocked by the protein kinase inhibitor K252a when added simultaneously, with minimal effect when added after 60 min