Chen-Kiang et al., Curr Opin Immunol 1993
(Virus Diseases) :
Transcription factors of the CCAAT/enhancer binding protein and AP-1 families, as well as the octamer binding proteins and the tumor suppressor gene product pRB , are regulated by interleukin-6 in a cell type specific manner, suggesting that they may play a role in the nuclear signaling by interleukin-6
Juge-Morineau et al., Leukemia & lymphoma 1997
(Cell Transformation, Neoplastic...) :
Absence of pRB may then induce an autocrine IL-6 expression in myeloma cells and contribute to the autonomous growth of MM