Hirabayashi et al., Development 2004
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Overexpression of Wnt7a or of a stabilized form of beta-catenin in mouse cortical NPC cultures induced neuronal differentiation even in the presence of Fgf2, a self-renewal promoting factor in this system
Kunke et al., Biochem Biophys Res Commun 2009
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Long-term activation of Wnt pathway by Wnt-7a or by treatment with GSK3 inhibitors promoted a moderate increase of the neuronal differentiation and blocked gliogenesis
Qu et al., Mol Cell Biol 2013
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Wnt7a stimulated neural stem cell proliferation by activating the ß-catenin-cyclin D1 pathway and promoted neuronal differentiation and maturation by inducing the ß-catenin-neurogenin 2 pathway