Gene interactions and pathways from curated databases and text-mining

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CYP2C19 — PTGS2

Text-mined interactions from Literome

Bertrand-Thiebault et al., Clin Exp Pharmacol Physiol 2004 (Varicose Veins) : In non-varicose veins, CYP1B1, CYP2C , CYP2E1 and CYP4A11 were detected , whereas CYP2J2, CYP3A5, COX-1 and COX-2 were detected almost exclusively in varicose veins
Michaelis et al., Arterioscler Thromb Vasc Biol 2005 : Overexpression of cytochrome P450 (CYP) 2C9 in endothelial cells increased cAMP levels, stimulated the cAMP-response element binding protein, and enhanced cyclooxygenase-2 (COX-2) promoter activity, protein expression, and prostacyclin production