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CYP2C19 — PTGS2
Text-mined interactions from Literome
Bertrand-Thiebault et al., Clin Exp Pharmacol Physiol 2004
(Varicose Veins) :
In non-varicose veins, CYP1B1,
CYP2C , CYP2E1 and CYP4A11 were
detected , whereas CYP2J2, CYP3A5, COX-1 and
COX-2 were detected almost exclusively in varicose veins
Michaelis et al., Arterioscler Thromb Vasc Biol 2005
:
Overexpression of
cytochrome P450 (CYP) 2C9 in endothelial cells increased cAMP levels, stimulated the cAMP-response element binding protein, and
enhanced cyclooxygenase-2 (COX-2) promoter activity, protein expression, and prostacyclin production