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RAC1 — SELE

Text-mined interactions from Literome

Chen et al., J Pharmacol Exp Ther 2003 : In contrast, Ad.N17Rac1 inhibited TNF-alpha induced NF-kappaB-driven HIV ( kappaB ) ( 4 ) -CAT and p288VCAM-Luc promoter activity, suggesting that N17Rac1 inhibits TNF-alpha induced VCAM-1, E-selectin , and ICAM-1 through suppressing NF-kappaB mediated transactivation
Koivisto et al., Exp Cell Res 2004 : The formation of E-lams was dependent on fibronectin binding integrins and normally regulated Rac1, and expression of either dominant negative or constitutively active forms of Rac1 prevented E-lam formation
Hamalukic et al., PloS one 2011 (Extravasation of Diagnostic and Therapeutic Materials...) : Administration of the widely used lipid lowering drug lovastatin prior to irradiation counteracts this process, likely by suppressing Rac1 regulated E-selectin expression following irradiation
Min et al., J Immunol 1997 : Transient overexpression of RAC1 or CDC42, but not RAS, constitutively activates JNK and augments TNF induced E-selectin transcription