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Gentle et al., J Biol Chem 2011
:
After receptor ligation, RIPK1 not only modulates activation of both canonical and NIK dependent NF-?B, but also regulates caspase-8 activation and cell death
Duprez et al., Immunity 2011
(Cecal Diseases...) :
An additional switch decides, depending on the cellular context, between caspase dependent apoptosis and RIP kinase ( RIPK ) -mediated necrosis, also termed necroptosis