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CD40LG — IL10

Text-mined interactions from Literome

Semnani et al., Infect Immun 2001 (Filariasis) : IL-10 was also inhibited ( P = 0.04 ) in response to CD40 ligand-IFN-gamma
McDowell et al., Infect Immun 2002 : Leishmania priming of human dendritic cells for CD40 ligand induced interleukin-12p70 secretion is strain and species dependent
Janssen et al., Am J Respir Cell Mol Biol 2002 (Asthma...) : This IL-10 production by the OVA-Mphi was dependent on MHC-TCR and CD86-CD28, but not CD80-CD28 or CD40-CD154 interactions
Möttönen et al., Arthritis Res 2002 (Arthritis, Rheumatoid) : Regulation of CD154 induced interleukin-12 production in synovial fluid macrophages
Wagner et al., Arterioscler Thromb Vasc Biol 2002 : One consequence of this statin dependent downregulation of CD40 expression was a decrease in CD40 ligand induced endothelial interleukin-12 expression
Mohty et al., J Leukoc Biol 2002 : Also, Thal induced a significant reduction of IL-10 production in response to the maturation inducing stimulus CD40L
Monti et al., Transplantation 2003 : CD40 ligand induced production of both IL-12 and IL-10 was reduced in rapa-DC, and allogeneic T lymphocyte responses were moderately impaired when rapa-DC were used as stimulator cells
Jeurissen et al., Eur J Immunol 2004 (Hypergammaglobulinemia) : Furthermore, we showed that caps-PS induce production of IL-4, IL-6, IL-10 , and IFN-gamma, and that this enhanced production was inhibited by blocking the CD40-CD40L interaction
Loskog et al., Clin Cancer Res 2005 (Carcinoma...) : CD40L stimulation of dendritic cells induces interleukin-12 expression that drives Th1 type of immune responses with activation of cytotoxic T cells
Good et al., J Immunol 2006 (Lupus Vulgaris) : Stimulation of human B cells with CD40L/IL-21 also induced IL-10 production and activation of STAT3
Murugaiyan et al., J Immunol 2007 (Neoplasms) : Lower levels of CD40L expression on T cells induced IL-10 mediated suppression of tumor regressing effector CD8 ( + ) T cells and higher productions of IL-4 and IL-10
Reddy et al., Cell Immunol 2007 : CNTO 1275 inhibited upregulation of CLA, IL-12R, IL-2Ralpha and CD40L expression and also inhibited IL-12- and IL-23 induced IFN-gamma, IL-17A, tumor necrosis factor (TNF)-alpha, IL-2, and IL-10 secretion
Bose et al., Hum Immunol 2007 (Carcinoma, Squamous Cell...) : Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with CD40-CD40L mediated endogenous production of interleukin-12
Jenkins et al., J Immunol 2008 (Schistosomiasis mansoni) : In this respect, optimal production of IL-5, IL-10 , and IL-13 was dependent upon CD154 expression by both CD4 ( + ) T cells and non-lymphoid cells
Díaz-Valdés et al., Hepatology 2011 : Similarly, when myeloid DCs were stimulated with CD40L in the presence of HCV core, p9 enhanced IL-12 production by inhibiting HCV core induced as well as CD40L induced IL-10
Melchers et al., Retrovirology 2011 : Dendritic cells secreted IL-6, IL-10 and IL-12 in response to stimulation by SOSIP.R6-IZ-CD40L and were able to activate naïve T cells
Zeitvogel et al., Exp Dermatol 2012 : Furthermore, we showed that this also applies to CD40L induced IL-10 expression in both investigated human APC subsets
da Silva et al., Immunobiology 2013 : CD40L did not stimulate the secretion of IL-10 , IL-12, TNF-a or IFN-? and did not stimulate migration toward CCL19 or CCL21
Kennedy et al., Eur J Immunol 1996 : CD40/CD40 ligand interactions are required for T cell dependent production of interleukin-12 by mouse macrophages
Urashima et al., Leuk Res 1996 : Interleukin-10+ CD40L triggered 100-fold increments in IgG, IgA and IgM secretion, but IL-10 suppressed IL-6 secretion triggered with CD40L +/- IL-4
Peng et al., Eur J Immunol 1996 : In this study we demonstrate that upon stimulation of human peripheral blood T cells through the T cell receptor (TCR)/CD3 complex, CD40/CD40L interaction strongly enhances the production of Th1 cytokines such as interleukin (IL)-2 and interferon (IFN)-gamma and Th2 cytokines such as IL-4, IL-5 and IL-10 by a direct effect on T cells
Chougnet et al., Eur J Immunol 1998 (HIV Infections...) : CD40L did not affect IL-10 production, whereas IFN-gamma significantly decreased it