Gene interactions and pathways from curated databases and text-mining

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ANG — CDKN1A

Text-mined interactions from Literome

Kim et al., J Biol Chem 2011 : A marked increase in the levels of p53 and p21 induced by Ang II was blunted by the treatment with GW501516
Paudel et al., J Virol 2012 : Silencing ANG or inhibiting its nuclear translocation resulted in decreased nuclear LANA-1 and ANG levels, decreased interactions between ANG-LANA-1, ANG-p53, and LANA-1-p53, the induction of p53, p21 , and Bax proteins, the increased cytoplasmic localization of p53, the downregulation of Bcl-2, the increased cleavage of caspase-3, and the apoptosis of cells