Tong et al., J Mol Endocrinol 2009
:
PTTG1 activates cyclin D3 and represses p21 expression, indicating a role in cell cycle regulation and cell senescence
Zhou et al., Mol Endocrinol 2009
(Pituitary Neoplasms) :
The presence of endogenous p53/p21 constrained the induction, whereas knocking down either p53 or p21 in HCT116 cells restored E2F1 induced hPTTG1 transactivation and expression