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CTSK — IL1A

Text-mined interactions from Literome

Fujisaki et al., Life Sci 2007 : In the presence of IL-1alpha , expression of CAII, cathepsin K , and MMP-9 was markedly increased in cells cultured with RANKL or M-CSF+RANKL, whereas expression was difficult to detect in cells cultured with IL-1alpha alone and M-CSF ... These results indicate that the expression of CAII, cathepsin K , and MMP-9 in RAW264.7 cells is not induced by M-CSF, but by RANKL in the presence of IL-1alpha
Jules et al., J Biol Chem 2012 : Here we show that although IL-1 can not activate the expression of the osteoclast genes encoding matrix metalloproteinase 9, cathepsin K , tartrate-resistant acid phosphatase, and carbonic anhydrase II in bone marrow macrophages ( BMMs ), RANKL renders these osteoclast genes responsive to IL-1