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IL1A — MTX1

Text-mined interactions from Literome

Chang et al., J Rheumatol 1992 (Arthritis, Rheumatoid) : Our results suggest that MTX may affect IL-1 production and IL-1 mediated events in some patients
Hobl et al., Clin Exp Rheumatol 2011 (Arthritis, Rheumatoid) : MTX reduces the production of pro-inflammatory cytokines such as interleukin (IL)-1 , IL-2, IL-6 and interferon (INF)-?, while the gene expression of anti-inflammatory Th2 cytokines like IL-4 and IL-10 is increased - altogether resulting in the anti-inflammatory effect
Segal et al., Arthritis Rheum 1990 (Lymphoma) : We have recently shown that methotrexate (MTX) inhibits interleukin-1 (IL-1) activity in vitro
Segal et al., Arthritis Rheum 1989 : To explore the possibility that the mechanism of action of methotrexate (MTX) in rheumatoid arthritis ( RA ) is related to modulation of interleukin-1 (IL-1), the effects of MTX on IL-1 production and activity were evaluated ... We did show, however, that MTX had an inhibitory effect on IL-1 activity in 2 assays that demonstrate 2 different functions of IL-1
van der Veen et al., Br J Rheumatol 1996 (Arthritis, Rheumatoid) : We studied the effects of MTX on proteoglycan ( PG ) turnover and interleukin-1 (IL-1)- and RA mononuclear cell ( RA-MNC ) -induced cartilage damage in human articular cartilage tissue cultures, and the effects of MTX on basal and RA-MNC influenced proliferation and differentiation of osteoblasts in cultures of human bone derived osteoblasts
Nose et al., J Rheumatol 1997 : To investigate the effects of salazosulfapyridine (SASP) and methotrexate (MTX) on interleukin (IL)-1beta treated rabbit chondrocytes