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P2RY6 — UTP18

Text-mined interactions from Literome

Chen et al., Br J Pharmacol 2001 : We have previously reported that G protein coupled P2Y(6) receptor activation by UTP potentiates lipopolysaccharide (LPS) induced I kappa B phosphorylation and degradation, and NF-kappa B activation in J774 macrophages
Guns et al., Br J Pharmacol 2006 : The vasodilator effect of UTP is probably mediated mainly by a P2Y6 ( like ) receptor
Nicholas et al., Mol Pharmacol 1996 : The data indicate that the P2Y2 receptor is activated with similar potencies by ATP and UTP but not by ADP or UDP ; the P2Y6 receptor is activated most potently by UDP but weakly by UTP , ATP, and ADP ; and the P2Y4 receptor is activated most potently by UTP, less potently by ATP, and not at all by nucleotide diphosphates
Nicholas et al., J Auton Pharmacol 1996 (Astrocytoma...) : 6. The P2Y6 receptor is activated most potently by UDP, but weakly or not at all by UTP , ADP and ATP