Gene interactions and pathways from curated databases and text-mining

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CD80 — IL7

Text-mined interactions from Literome

Costello et al., Eur Cytokine Netw 1999 (Burkitt Lymphoma...) : In the corresponding, co-cultured T lymphocyte population, IL-7 more particularly increased B7-1/CD80 and CD58/LFA-3 expression
Blanchet et al., Am J Respir Crit Care Med 2004 (Alveolitis, Extrinsic Allergic) : To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells
Dennig et al., Cell Immunol 1994 : IL-7 induces surface expression of B7/BB1 on pre-B cells and an associated increase in their costimulatory effects on T cell proliferation ... These results suggest that B7/BB1 negative pre-B cells may acquire the surface expression of B7/BB1 upon stimulation with IL-7 , a process which is associated with increased costimulatory function for T cell proliferation