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EZR — RHO
Text-mined interactions from Literome
Lee et al., J Cell Biol 2004
(Lymphoma, T-Cell) :
Phosphorylated
ezrin associates with Dbl through its NH2-terminal domain and
causes Rho activation
Rossy et al., Exp Cell Res 2007
(Carcinoma 256, Walker) :
We further show that endogenous
ezrin and moesin are phosphorylated and that activities of PI-3 kinase,
Rho and Rac, but not of Rho-kinase, are
required for this C-terminal phosphorylation
Hébert et al., J Immunol 2008
:
Rho-ROCK dependent
ezrin-radixin-moesin phosphorylation regulates Fas mediated apoptosis in Jurkat cells ... Indeed, inhibition of either
Rho or ROCK
prevents ezrin and moesin phosphorylation, abrogates the formation of Fas aggregates, and interferes with caspase-8 activation
Tang et al., J Biol Chem 2009
(Nasopharyngeal Neoplasms...) :
Furthermore, the inhibitory effects of berberine on
phospho-Ezrin were
dependent on the suppression of
Rho kinase activity
Takahashi et al., J Biol Chem 1997
:
Direct interaction of the Rho GDP dissociation inhibitor with
ezrin/radixin/moesin initiates the activation of the
Rho small G protein